As their lives take them in different directions, Lena, Tibby, Carmen, and Bridget discover many more things about themselves and the importance of their relationship with each other.
The members of the Sisterhood of the Traveling Pants graduate from high school and spend their last summer before college learning about life and themselves.
During their first summer apart, four teenage girls, best friends since earliest childhood, stay in touch through a shared pair of secondhand jeans that magically adapts to each of their figures and affects their attitudes to their different summer experiences.