The show follows Meyer and her staff as they attempt to make their mark and leave a lasting legacy, without getting tripped up in the day-to-day political games that define Washington.

After the death of her husband, Claire Underwood becomes the first female President of the United States, but faces formidable threats to her legacy.

As midterm elections loom, Vice President Meyer is scoring higher ratings than the President in several popularity polls, which she hopes will boost her influence and help her curry favor with the chief executive. But despite her best intentions, even the most banal actions can set off unexpected and often disastrous consequences. Her staff is close at hand with a laugh-out-loud combination of personal problems and government-insider antics.